TyG index and MAFLD severity are associated with subclinical LV dysfunction in T2DM patients: a cross−sectional study

Fib-4 index and TyG index are independent predictors of SLVD in T2DM, and their coexistence exerts a synergistic effect. Combined assessment provides a simple, non-invasive tool for early risk stratification, highlighting the clinical importance of the liver-heart axis in identifying SLVD.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-01-27
DOI
https://doi.org/10.3389/fendo.2025.1749989
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

TyG index and MAFLD severity are associated with subclinical LV dysfunction in T2DM patients: a cross−sectional study

Liangyun Guo, Yun Deng, Long Huang, Xiangsui Hu et al.
Frontiers in Endocrinology
Liver Disease Diagnosis and Treatment
article

TyG index and MAFLD severity are associated with subclinical LV dysfunction in T2DM patients: a cross−sectional study

Liangyun Guo, Yun Deng, Long Huang, Xiangsui Hu, Chunquan Zhang, Lingmin Liao, Hanwei Chen, Ziying Wang, Shengbo Liu
article en

Abstract

Fib-4 index and TyG index are independent predictors of SLVD in T2DM, and their coexistence exerts a synergistic effect. Combined assessment provides a simple, non-invasive tool for early risk stratification, highlighting the clinical importance of the liver-heart axis in identifying SLVD.

Frontiers in EndocrinologyVol. 16
Nanchang University (CN), General Electric (Spain) (ES), First Affiliated Hospital of Jiangxi Medical College (CN), Second Affiliated Hospital of Nanchang University (CN), Second Affiliated Hospital of Xi'an Jiaotong University (CN), Gaozhou People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 77%
Liver Disease Diagnosis and Treatment
DOIOpen Access PDFOpenAlex
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TyG index and MAFLD severity are associated with subclinical LV dysfunction in T2DM patients: a cross−sectional study — Liangyun Guo, Yun Deng, et al. · Frontiers in Endocrinology (2026) | TGRS Research Map | TGRS