The Paradoxical Effect of Cannabis Use on Cognition in Chronic Psychotic Disorders
Contrary to the prevailing assumption that cannabis use exacerbates cognitive decline, our findings indicate an unexpected association between cannabis use and preserved cognitive functioning in psychosis. These results underscore the need to consider dosage, frequency, and cannabinoid composition (THC/CBD ratio) when interpreting cannabis-related cognitive outcomes in psychotic disorders.
Authors
- Carmine Gelormini
- Fatime Elezi
- Federico Fiori Nastro
- Fiorela Gorea
- Martina Pelle
- Giorgio Di Lorenzo
- Michele Ribolsi
Institutions
- University of Rome Tor Vergata (IT)
- Reykjavík University (IS)
- Università Campus Bio-Medico (IT)
- Mother Teresa Hospital (AL)
- Fondazione Santa Lucia (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Link Campus University (IT)
Publication Details
- Journal
- Pathophysiology
- Published
- 2026-01-27
- DOI
- https://doi.org/10.3390/pathophysiology33010011
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00