Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals the transcriptome profile of Microtus fortis immune cells during the early phase of infection with Schistosoma japonicum
Together, our results suggest that both the innate and adaptive immune responses were activated in the peripheral blood of <i>M. fortis</i> at 10 dpi, while their activation was not obvious in Kunming mice at the same moment.
Authors
- Zhuolin Li
- Bo Li
- Zhijun Zhou
- Xiaohui Yang
- Huilan Wang
- Xiang Wu
- Shukun Zhong
- Yuehui Li
- Shuaiqin Huang
- Xianshu Liu
- Nouhoum Dibo
- Jiajing Zhang
Institutions
- Central South University (CN)
- Model Animal Research Center (CN)
- Hunan Provincial People's Hospital (CN)
- Centre for Schistosomiasis & Parasitology (CM)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-01-27
- DOI
- https://doi.org/10.3389/fcimb.2025.1739541
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Central South University
- National Key Research and Development Program of China