Complex network behavior in epileptic patients treated with Vagus Nerve Stimulation (VNS): VNS responders exhibit a unique pattern, different from VNS non-responders and healthy controls

The VNS responders exhibit more differences when compared to HCs than VNS non-responders. These differences can be observed in RPW, but they become more pronounced when Entropy analysis is applied. It seems that the distinct response to hyperventilation is present in both VNS responders and non-responders, differentiating them from HCs. However, the binding of this response to frequency bands differs among VNS responders and non-responders. In particular, the reaction among the VNS responders is strongly associated with the alpha frequency band.