Spinal anesthesia in a patient with Andersen-Tawil syndrome

Andersen-Tawil syndrome (ATS) is a rare autosomal-dominant disorder characterized by periodic paralysis, ventricular arrhythmia, QT prolongation, and craniofacial or skeletal anomalies, complicating perioperative management.Here, we describe the successful use of spinal anesthesia in a 26-year-old man with genetically confirmed ATS, who underwent excision of a left popliteal myoepithelial sarcoma.Continuous electrocardiography, invasive arterial pressure monitoring, and intraoperative arterial blood gas analyses revealed relatively stable electrolyte levels and hemodynamic parameters.Surgery and recovery were uneventful.Four months after treatment, a repeat surgery for local recurrence was performed under spinal anesthesia without complications.Overall, cautious perioperative monitoring allowed spinal anesthesia to be performed safely in this patient.