Multifaceted antimicrobial mechanisms of NCR147-derived peptides from Medicago truncatula

These findings reveal that NCR147-derived peptides function via a multihit mechanism and highlight the therapeutic promise of plant-derived AMPs as next-generation antimicrobials with reduced risk of resistance development.

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Publication Details

Journal
Frontiers in Microbiology
Published
2026-01-27
DOI
https://doi.org/10.3389/fmicb.2025.1720738
Primary Topic
Antimicrobial Peptides and Activities
Type
article
Field-Weighted Citation Impact
0.00

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article

Multifaceted antimicrobial mechanisms of NCR147-derived peptides from Medicago truncatula

Edit Tímár, Alexandra Pál, Sándor Jenei, Nóra Igaz et al.
Frontiers in Microbiology
Antimicrobial Peptides and Activities
article

Multifaceted antimicrobial mechanisms of NCR147-derived peptides from Medicago truncatula

Edit Tímár, Alexandra Pál, Sándor Jenei, Nóra Igaz, Rui M. Lima, Zoltán Bozsó, Éva Hunyadi-Gulyás, Ilona Pfeiffer, Gábor K. Tóth, Dian H. O. Howan, Éva Kondorosi, Hilda Tiricz, Ildikó Domonkos
article en

Abstract

These findings reveal that NCR147-derived peptides function via a multihit mechanism and highlight the therapeutic promise of plant-derived AMPs as next-generation antimicrobials with reduced risk of resistance development.

Frontiers in MicrobiologyVol. 16
Semmelweis University (HU), University of Szeged (HU), Abterra Biosciences (United States) (US), Institute of Plant Protection (CN), Institute of Plant Biology (HU), MTA-SZTE Research Group on Artificial Intelligence (HU), Plant Protection Institute (HU)
Fondazione Internazionale Premio Balzan, Nemzeti Kutatási Fejlesztési és Innovációs Hivatal
Openalex Percentile: Top 75%
Antimicrobial Peptides and Activities
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