XCPP: A Multi-model Explainable Deep Learning Framework forAccurate Identification of Cell-Penetrating Peptides from StructuredSequence Features
Deep learning in this case has created a framework that can accurately identify CPPs. The CNN model also has additional features that make it ideal for use in drug delivery, molecular diagnostics, and personalized medicine. SHAP-based XAI further adds explainability, increasing trust in the model's predictions.
Authors
- Fahad Alturise
- Tamim Alkhalifah
- Yaser Daanial Khan
- Hafsah Riasat
Institutions
- Qassim University (SA)
- University of Management and Technology (PK)
- Buraydah Colleges (SA)
Publication Details
- Journal
- Current Drug Targets
- Published
- 2026-01-20
- DOI
- https://doi.org/10.2174/0113894501416864251212082231
- Primary Topic
- Machine Learning in Bioinformatics
- Type
- article
- Field-Weighted Citation Impact
- 0.00