The Structural Analogy of MASP-2 with Thrombin and MASP-1 Reveals Strong Binding with PAR4

Our findings may pave the way for future investigations into the signaling mechanisms and therapeutic potential of PAR4-mediated inflammatory diseases.

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Publication Details

Journal
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Published
2026-01-20
DOI
https://doi.org/10.2174/0118715230411505251126063432
Primary Topic
Blood Coagulation and Thrombosis Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

The Structural Analogy of MASP-2 with Thrombin and MASP-1 Reveals Strong Binding with PAR4

Sadhana Sharma, Krishnan Hajela, Sumati Hajela, Mridul Madhuri et al.
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Blood Coagulation and Thrombosis Mechanisms
article

The Structural Analogy of MASP-2 with Thrombin and MASP-1 Reveals Strong Binding with PAR4

Sadhana Sharma, Krishnan Hajela, Sumati Hajela, Mridul Madhuri, Uzma Saqib
article en

Abstract

Our findings may pave the way for future investigations into the signaling mechanisms and therapeutic potential of PAR4-mediated inflammatory diseases.

Anti-Inflammatory & Anti-Allergy Agents in Medicinal ChemistryVol. 25
Devi Ahilya Vishwavidyalaya (IN), Rani Durgavati University (IN), All India Institute of Medical Sciences (IN)
Openalex Percentile: Top 79%
Blood Coagulation and Thrombosis Mechanisms
DOISourceOpenAlex
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