Corneal Stromal Thinning and Posterior Irregularity After DMEK: Clinical Observations and Biophysical Hypotheses
Greater reductions in corneal thickness are associated with postoperative stromal thinning and hyperopic shift after DMEK. Preoperative stromal ripples are associated with greater reductions in corneal thickness after DMEK. Stromal remodeling appears influenced by endothelial recovery and preoperative biomechanical status, supporting emerging hypotheses on keratocyte loss and osmotic imbalance.
Authors
- Sally Hayes
- Alfredo Borgia
- Francesco Semeraro
- Filippo Lozza
- Phil Lewis
- Vito Romano
- Sabrina Vaccaro
- Stephen B. Kaye
- Keith Meek
- Neethi Thathapudi
- David Lockington
- Matteo Airaldi
Institutions
- University of Liverpool (GB)
- Aintree University Hospitals NHS Foundation Trust (GB)
- Gartnavel General Hospital (GB)
- Hôpital Maisonneuve-Rosemont (CA)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Ospedale di Monfalcone (IT)
- Université de Montréal (CA)
- Cardiff University (GB)
- University of Brescia (IT)
Publication Details
- Journal
- Cornea
- Published
- 2026-01-27
- DOI
- https://doi.org/10.1097/ico.0000000000004084
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00