Application and safety analysis of paravertebral block with dezocine and ropivacaine in video-assisted thoracoscopic surgery for lung cancer

When used in TPVB for VATS, different doses of dezocine combined with ropivacaine offer distinct short-term postoperative benefits: the 0.1 mg⋅kg<sup>-1</sup> dezocine results in faster postoperative recovery, whereas the 0.15 mg⋅kg<sup>-1</sup> dezocine demonstrates superior postoperative analgesic efficacy and inflammation suppression. Both doses exhibited high safety profiles, providing certain references for the selection of clinical anesthesia protocols.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-27
DOI
https://doi.org/10.3389/fmed.2025.1723385
Primary Topic
Cancer, Stress, Anesthesia, and Immune Response
Type
article
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article

Application and safety analysis of paravertebral block with dezocine and ropivacaine in video-assisted thoracoscopic surgery for lung cancer

Faju Wan, Yong Wu, Dengxue Gan, Hui Liu
Frontiers in Medicine
Cancer, Stress, Anesthesia, and Immune Response
article

Application and safety analysis of paravertebral block with dezocine and ropivacaine in video-assisted thoracoscopic surgery for lung cancer

Faju Wan, Yong Wu, Dengxue Gan, Hui Liu
article en

Abstract

When used in TPVB for VATS, different doses of dezocine combined with ropivacaine offer distinct short-term postoperative benefits: the 0.1 mg⋅kg<sup>-1</sup> dezocine results in faster postoperative recovery, whereas the 0.15 mg⋅kg<sup>-1</sup> dezocine demonstrates superior postoperative analgesic efficacy and inflammation suppression. Both doses exhibited high safety profiles, providing certain references for the selection of clinical anesthesia protocols.

Frontiers in MedicineVol. 12
Army Medical University (CN), Affiliated Hospital of Southwest Medical University (CN), Third People 's Hospital of Chongqing (CN), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Zigong First People's Hospital (CN), Chongqing Medical University (CN)
Good health and well-being
Openalex Percentile: Top 77%
Cancer, Stress, Anesthesia, and Immune Response
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