Limited Sensitivity of Ultrasound‐Guided Fine‐Needle Aspiration Cytology for Occult Nodal Metastases in Early‐Stage Oral Squamous Cell Carcinoma
In patients with early-stage oral cavity squamous cell carcinoma and a clinically negative neck, US-FNAC demonstrates high specificity but limited sensitivity and negative predictive value. These findings indicate that US-FNAC alone is insufficient to exclude occult nodal metastases and should be regarded as an adjunctive diagnostic tool rather than a stand-alone nodal staging strategy.
Authors
- Gerben E. Breimer
- Jan Willem Dankbaar
- Roosmarijn S. Tellman
- Frank A. Pameijer
- Sammy M. Schouten
- Dominique N. V. Donders
- Bart de Keizer
- Remco de Bree
Institutions
- Utrecht University (NL)
- University Medical Center Utrecht (NL)
Publication Details
- Journal
- Head & Neck
- Published
- 2026-01-27
- DOI
- https://doi.org/10.1002/hed.70183
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00