IgA-Producing B Cells Exert Regulatory Function Through Granzyme B in Kidney Allograft Tolerance
These data show a strong association between IgA+ and GZMB+ Bregs, particularly in tolerant kidney transplant recipients with higher GZMB and IgA expression and greater suppressive properties.
Authors
- Richard Danger
- Nicolas Sailliet
- François Brinas
- Magali Giral
- Nicolas Degauque
- Clarisse Kerleau
- Mélanie Chesneau
- Sophie Brouard
- Laureline Berthelot
- Léo Boussamet
- Camille Mathé
- Luc Colas
- Amandine Dupuy
- Hoa Le Mai (ORCID: https://orcid.org/0000-0003-2099-4420)
- Laura Cappelier
- Gaelle Tilly
- Nataliya Yeremenko
Institutions
- Inserm (FR)
- Centre Hospitalier Universitaire de Nantes (FR)
- Institut de Transplantation Urologie en Nephrologie (FR)
- Nantes Université (FR)
Publication Details
- Journal
- Kidney360
- Published
- 2026-01-27
- DOI
- https://doi.org/10.34067/kid.0000001054
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 0.00