Periprosthetic Metabolic Activity After Total Ankle Arthroplasty: Cross-Sectional <sup>18</sup> F-NaF PET/CT Data From Asymptomatic Patients at 6-24 Months

The present study demonstrates that in asymptomatic patients, periprosthetic tracer uptake peaks at 12 months and remains elevated up to 24 months following modern fixed-bearing TAA. In both the tibia and talus, uptake decreased between 12 and 24 months. Talar uptake was higher than tibial uptake at 12, 18, and 24 months. Our findings suggest that radionuclide bone scintigraphy should be cautiously interpreted especially when performed within 2 years of TAA.

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Publication Details

Journal
Foot & Ankle International
Published
2026-01-27
DOI
https://doi.org/10.1177/10711007251394715
Citations
1
Primary Topic
Foot and Ankle Surgery
Type
article
Field-Weighted Citation Impact
39.58
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article

Periprosthetic Metabolic Activity After Total Ankle Arthroplasty: Cross-Sectional 18 F-NaF PET/CT Data From Asymptomatic Patients at 6-24 Months

Constantine A. Demetracopoulos, Alan Wu, Scott J. Ellis, Arindam RoyChoudhury et al.
1 citations
Foot & Ankle International
Foot and Ankle Surgery
39.58
article

Periprosthetic Metabolic Activity After Total Ankle Arthroplasty: Cross-Sectional 18 F-NaF PET/CT Data From Asymptomatic Patients at 6-24 Months

Constantine A. Demetracopoulos, Alan Wu, Scott J. Ellis, Arindam RoyChoudhury, Jonathan P. Dyke, Elizabeth A. Cody, Silvina P. Dutruel, Lavan Rajan
article en
1 citations

Abstract

The present study demonstrates that in asymptomatic patients, periprosthetic tracer uptake peaks at 12 months and remains elevated up to 24 months following modern fixed-bearing TAA. In both the tibia and talus, uptake decreased between 12 and 24 months. Talar uptake was higher than tibial uptake at 12, 18, and 24 months. Our findings suggest that radionuclide bone scintigraphy should be cautiously interpreted especially when performed within 2 years of TAA.

Foot & Ankle InternationalVol. 47(2)
University of Maryland, Baltimore (US), Hospital for Special Surgery (US), University of Maryland Medical Center (US), Cornell University (US), Weill Cornell Medicine (US)
Openalex Percentile: Top 1%
Foot and Ankle Surgery
39.58
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Periprosthetic Metabolic Activity After Total Ankle Arthroplasty: Cross-Sectional <sup>18</sup> F-NaF PET/CT Data From Asymptomatic Patients at 6-24 Months — Constantine A. Demetracopoulos, Alan Wu, et al. · Foot & Ankle International (2026) | TGRS Research Map | TGRS