Weight trajectories throughout adulthood and prostate cancer incidence, aggressiveness, and death in 258 494 men

The associations observed for incident PCa appear to be influenced by PSA testing uptake; however, the extent to which detection bias contributes remains uncertain. Conversely, late midlife weight gain was associated with an elevated risk of PCa death, underscoring the importance of weight management during this period as a potentially modifiable factor for reducing PCa death.

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Publication Details

Journal
JNCI Journal of the National Cancer Institute
Published
2026-01-19
DOI
https://doi.org/10.1093/jnci/djag014
Primary Topic
Cancer Risks and Factors
Type
article
Field-Weighted Citation Impact
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article

Weight trajectories throughout adulthood and prostate cancer incidence, aggressiveness, and death in 258 494 men

Sölve Elmståhl, Kate Tilling, Hannu Kankaanranta, Abbas Chabok et al.
JNCI Journal of the National Cancer Institute
Cancer Risks and Factors
article

Weight trajectories throughout adulthood and prostate cancer incidence, aggressiveness, and death in 258 494 men

Sölve Elmståhl, Kate Tilling, Hannu Kankaanranta, Abbas Chabok, Bright I Nwaru, Innocent B Mboya, Sara Hägg, Karl Michaëlsson, Linnea Hedman, Marisa Da Silva, Sylvia H J Jochems, Ahmed Elhakeem, Tanja Stocks, Ming Sun, Pär Stattin, Ylva T Lagerros, Josef Fritz, Helena Backman, Lena Lönnberg, Jens Wahlström, Christel Häggström, Patrik K E Magnusson
article en

Abstract

The associations observed for incident PCa appear to be influenced by PSA testing uptake; however, the extent to which detection bias contributes remains uncertain. Conversely, late midlife weight gain was associated with an elevated risk of PCa death, underscoring the importance of weight management during this period as a potentially modifiable factor for reducing PCa death.

JNCI Journal of the National Cancer Institute
Uppsala University (SE), National Academy of Medicine (US), Innsbruck Medical University (AT), Tampere University (FI), Seinäjoki University of Applied Sciences (FI), Malmö University (SE), Lund University (SE), Universität Innsbruck (AT), Utrecht University (NL), Karolinska Institutet (SE), University of Bristol (GB), Glanrhyd Hospital (GB), Wallenberg Wood Science Center (SE), Mälardalen University (SE), Kilimanjaro Christian Medical Centre (TZ), Africa Academy for Public Health (TZ), MRC Epidemiology Unit (GB), Halmstad University (SE), University of Gothenburg (SE), Umeå University (SE)
Good health and well-being
Openalex Percentile: Top 77%
Cancer Risks and Factors
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