ST2 Signaling Regulates Innate Immune Responses in Kidney Injury

We conclude that the IL-33/ST2 axis is essential for regulating macrophage function and contributes to regulating tissue homeostasis following renal injury.

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-01-26
DOI
https://doi.org/10.64898/2026.01.24.701541
Primary Topic
IL-33, ST2, and ILC Pathways
Type
article
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ST2 Signaling Regulates Innate Immune Responses in Kidney Injury

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ST2 Signaling Regulates Innate Immune Responses in Kidney Injury

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article en

Abstract

We conclude that the IL-33/ST2 axis is essential for regulating macrophage function and contributes to regulating tissue homeostasis following renal injury.

bioRxiv (Cold Spring Harbor Laboratory)
Virginia Commonwealth University (US), Center for Neuroscience and Regenerative Medicine (US), University of Virginia (US), Carilion Clinic (US)
Life below water
Openalex Percentile: Top 77%
IL-33, ST2, and ILC Pathways
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