CyTOF profiling identifies location-specific peripheral immune checkpoint and immune cell subset in mild ischemic stroke

Peripheral immune remodeling in mild ischemic stroke displays clear infarct location-specific trajectories. These findings highlight infarct topology as a critical determinant of post-stroke immune regulation and support the development of location-adapted immunomodulatory strategies.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-27
DOI
https://doi.org/10.3389/fimmu.2026.1739324
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00

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article

CyTOF profiling identifies location-specific peripheral immune checkpoint and immune cell subset in mild ischemic stroke

Baohui Xu, Heng Zhao, Yang Yao, Jing Zhao et al.
Frontiers in Immunology
Neuroinflammation and Neurodegeneration Mechanisms
article

CyTOF profiling identifies location-specific peripheral immune checkpoint and immune cell subset in mild ischemic stroke

Baohui Xu, Heng Zhao, Yang Yao, Jing Zhao, Guofeng Wu, Likun Wang, Hang Hang, Cuiying Liu
article en

Abstract

Peripheral immune remodeling in mild ischemic stroke displays clear infarct location-specific trajectories. These findings highlight infarct topology as a critical determinant of post-stroke immune regulation and support the development of location-adapted immunomodulatory strategies.

Frontiers in ImmunologyVol. 17
Capital Medical University (CN), Tianjin Medical University General Hospital (CN), Tongren Hospital (CN), Affiliated Hospital of Guizhou Medical University (CN), Ministry of Science and Technology (VN), Stanford University (US)
Health Commission of Guizhou Province, National Natural Science Foundation of China, Guizhou Medical University
Openalex Percentile: Top 82%
Neuroinflammation and Neurodegeneration Mechanisms
DOIOpen Access PDFOpenAlex
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CyTOF profiling identifies location-specific peripheral immune checkpoint and immune cell subset in mild ischemic stroke — Baohui Xu, Heng Zhao, et al. · Frontiers in Immunology (2026) | TGRS Research Map | TGRS