Spatially aware radiomics integrating anatomical knowledge to improve lymph node malignancy prediction in head and neck cancer
This study demonstrates that incorporating lymphatic anatomy and clinical context into radiomics models significantly improves predictive performance. The proposed approach enhances interpretability, aligns with clinical workflows, and holds promises for personalized radiation therapy planning.
Authors
- Sepeadeh Radpour
- Michael Dohopolski
- David Sher
- Jing Wang
- Liyuan Chen
Institutions
- Southwestern Medical Center (US)
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Journal of Applied Clinical Medical Physics
- Published
- 2026-01-27
- DOI
- https://doi.org/10.1002/acm2.70483
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Texas Southwestern Medical Center
- National Institutes of Health