Real-world evidence of clinical outcomes and adherence to ofatumumab in the UK and the impact of a patients support programme: A retrospective, non-interventional cohort study

This study provides evidence of good adherence for RMS patients using ofatumumab. Further, there is evidence of clinical effectiveness based on reduction in ARR post-ofatumumab initiation, as well as tolerability and a favourable safety profile. The results of this study support the continued use of ofatumumab in providing effective RMS disease management in the UK NHS.

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Publication Details

Journal
Multiple Sclerosis and Related Disorders
Published
2026-01-27
DOI
https://doi.org/10.1016/j.msard.2026.107030
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
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article

Real-world evidence of clinical outcomes and adherence to ofatumumab in the UK and the impact of a patients support programme: A retrospective, non-interventional cohort study

Owen Pearson, David Cottrell, Ruth Hamlin, Pyry Kivi et al.
Multiple Sclerosis and Related Disorders
Rheumatoid Arthritis Research and Therapies
article

Real-world evidence of clinical outcomes and adherence to ofatumumab in the UK and the impact of a patients support programme: A retrospective, non-interventional cohort study

Owen Pearson, David Cottrell, Ruth Hamlin, Pyry Kivi, David Paling, Sarah Al-Azki, Agne Straukiene, Nazanin Kondori, Colin O'Leary, Wendy Rice
article en

Abstract

This study provides evidence of good adherence for RMS patients using ofatumumab. Further, there is evidence of clinical effectiveness based on reduction in ARR post-ofatumumab initiation, as well as tolerability and a favourable safety profile. The results of this study support the continued use of ofatumumab in providing effective RMS disease management in the UK NHS.

Multiple Sclerosis and Related DisordersVol. 107
Swansea Bay University Health Board (GB), North Bristol NHS Trust (GB), Royal United Hospital (GB), Southmead Hospital (GB), Royal Hallamshire Hospital (GB), Torbay Hospital (GB), IQVIA (United Kingdom) (GB), IQVIA (United States) (US), Novartis (United Kingdom) (GB), Torbay and South Devon NHS Foundation Trust (GB), Royal United Hospital Bath NHS Trust (GB)
Good health and well-being
Openalex Percentile: Top 78%
Rheumatoid Arthritis Research and Therapies
DOIOpen Access PDFOpenAlex
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Real-world evidence of clinical outcomes and adherence to ofatumumab in the UK and the impact of a patients support programme: A retrospective, non-interventional cohort study — Owen Pearson, David Cottrell, et al. · Multiple Sclerosis and Related Disorders (2026) | TGRS Research Map | TGRS