Early risk stratification of sepsis-related liver injury via machine learning: a multicohort study

Our study explored ML-based models for predicting SRLI among sepsis at an earlier stage and the performance of random forest model ranked best. The significant predictive contribution of prothrombin time highlights its potential as a key monitoring marker for early risk stratification in septic patients.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-27
DOI
https://doi.org/10.3389/fmed.2026.1649101
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Early risk stratification of sepsis-related liver injury via machine learning: a multicohort study

Tingbin Xie, Pinwen Zhou, Jiaqi Wang, Li Zhang et al.
Frontiers in Medicine
Sepsis Diagnosis and Treatment
article

Early risk stratification of sepsis-related liver injury via machine learning: a multicohort study

Tingbin Xie, Pinwen Zhou, Jiaqi Wang, Li Zhang, Xinying Wang, Xin Chen, Wei Ma
article en

Abstract

Our study explored ML-based models for predicting SRLI among sepsis at an earlier stage and the performance of random forest model ranked best. The significant predictive contribution of prothrombin time highlights its potential as a key monitoring marker for early risk stratification in septic patients.

Frontiers in MedicineVol. 13
Nanjing General Hospital of Nanjing Military Command (CN), Nanjing Medical University (CN)
Openalex Percentile: Top 77%
Sepsis Diagnosis and Treatment
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