Large Language Model–Based Chatbots and Agentic AI for Mental Health Counseling: Systematic Review of Methodologies, Evaluation Frameworks, and Ethical Safeguards

LLM-based MH counseling chatbots show promise for scalable and personalized support, but current evidence is limited by heterogeneous study designs, minimal external validation, and inconsistent reporting of safety and governance practices. Future work should prioritize clinically grounded evaluation frameworks, transparent reporting of model and prompt configurations, and stronger validation using standardized outcomes to support safe, reliable, and regulatory-ready deployment.

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Publication Details

Journal
JMIR AI
Published
2026-01-27
DOI
https://doi.org/10.2196/80348
Primary Topic
Digital Mental Health Interventions
Type
article
Field-Weighted Citation Impact
0.00
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article

Large Language Model–Based Chatbots and Agentic AI for Mental Health Counseling: Systematic Review of Methodologies, Evaluation Frameworks, and Ethical Safeguards

Ha Na Cho, Jiayuan Wang, Di Hu, Kai Zheng
JMIR AI
Digital Mental Health Interventions
article

Large Language Model–Based Chatbots and Agentic AI for Mental Health Counseling: Systematic Review of Methodologies, Evaluation Frameworks, and Ethical Safeguards

Ha Na Cho, Jiayuan Wang, Di Hu, Kai Zheng
article en

Abstract

LLM-based MH counseling chatbots show promise for scalable and personalized support, but current evidence is limited by heterogeneous study designs, minimal external validation, and inconsistent reporting of safety and governance practices. Future work should prioritize clinically grounded evaluation frameworks, transparent reporting of model and prompt configurations, and stronger validation using standardized outcomes to support safe, reliable, and regulatory-ready deployment.

JMIR AIVol. 5
University of California, Irvine (US)
Gender equality
Openalex Percentile: Top 80%
Digital Mental Health Interventions
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