Non-thyroidal illness syndrome predicts poor prognosis in hepatocellular carcinoma patients treated with atezolizumab and bevacizumab

Thyroid dysfunction during Ate/Bev therapy is prognostically significant. NTIS reflects systemic deterioration and portends poor survival, whereas thyroid AEs may suggest favorable immune activation. Routine monitoring of thyroid function may aid in risk stratification.

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Publication Details

Journal
Cancer Immunology Immunotherapy
Published
2026-01-27
DOI
https://doi.org/10.1007/s00262-026-04308-z
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Non-thyroidal illness syndrome predicts poor prognosis in hepatocellular carcinoma patients treated with atezolizumab and bevacizumab

Chen-Chun Lin, Chung-Wei Su, Yi-Chung Hsieh, Po-Ting Lin et al.
Cancer Immunology Immunotherapy
Thyroid Cancer Diagnosis and Treatment
article

Non-thyroidal illness syndrome predicts poor prognosis in hepatocellular carcinoma patients treated with atezolizumab and bevacizumab

Chen-Chun Lin, Chung-Wei Su, Yi-Chung Hsieh, Po-Ting Lin, Chun-Yen Lin, I.-Wen Chen, Wei Teng, Wei-Ting Chen, Cheng-Wei Lin, Tsung-Han Wu, Shi-Ming Lin
article en

Abstract

Thyroid dysfunction during Ate/Bev therapy is prognostically significant. NTIS reflects systemic deterioration and portends poor survival, whereas thyroid AEs may suggest favorable immune activation. Routine monitoring of thyroid function may aid in risk stratification.

Cancer Immunology ImmunotherapyVol. 75(2)
Chang Gung University (TW), National Tsing Hua University (TW), Chang Gung Memorial Hospital (TW), Taipei Municipal YangMing Hospital (TW), Linkou Chang Gung Memorial Hospital (TW)
Chang Gung Medical Foundation
No poverty
Openalex Percentile: Top 78%
Thyroid Cancer Diagnosis and Treatment
DOIOpen Access PDFOpenAlex
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