Graft Choice for Anterior Cruciate Ligament Reconstruction: Superior Tendon-to-Bone Incorporation With Soft-tissue Autograft Compared With Allograft and Hybrid Graft in a Rat Model

This preclinical study, conducted in a rat model, provides mechanistic evidence that autografts exhibit superior biological incorporation and mechanical integrity, supporting the existing clinical preference for autograft in ACLR and helping inform graft selection.

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Publication Details

Journal
The American Journal of Sports Medicine
Published
2026-01-27
DOI
https://doi.org/10.1177/03635465251403553
Primary Topic
Knee injuries and reconstruction techniques
Type
article
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article

Graft Choice for Anterior Cruciate Ligament Reconstruction: Superior Tendon-to-Bone Incorporation With Soft-tissue Autograft Compared With Allograft and Hybrid Graft in a Rat Model

Kai Shen, Chien-Wei Lee, Hongtao Xu, Siqi Yang et al.
The American Journal of Sports Medicine
Knee injuries and reconstruction techniques
article

Graft Choice for Anterior Cruciate Ligament Reconstruction: Superior Tendon-to-Bone Incorporation With Soft-tissue Autograft Compared With Allograft and Hybrid Graft in a Rat Model

Kai Shen, Chien-Wei Lee, Hongtao Xu, Siqi Yang, Zhikuan Li, Qing Wang, Huanghe Song, Hao Liu, Hao Zhou, Rui Liu, Guoyong Yin, Dunming Guo, Xiaoyuan Gu, Xusheng Bo, Yu Liu, Jiangtao Dong
article en

Abstract

This preclinical study, conducted in a rat model, provides mechanistic evidence that autografts exhibit superior biological incorporation and mechanical integrity, supporting the existing clinical preference for autograft in ACLR and helping inform graft selection.

The American Journal of Sports MedicineVol. 54(2)
Hebei Medical University (CN), China Medical University (TW), Third Hospital of Hebei Medical University (CN), Nanjing Drum Tower Hospital (CN), China Medical University Hospital (TW), Jiangsu Province Hospital (CN), Nanjing Medical University (CN)
Openalex Percentile: Top 77%
Knee injuries and reconstruction techniques
DOISourceOpenAlex
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