Lipoprotein(a) Concentration and Achieving Target Values of Low-Density Lipoprotein Cholesterol Calculated by Different Equations

Comparison of LDL-C concentrations calculated by Friedewald, Martin-Hopkins, and Sampson equations showed high consistency in patients without elevated triglycerides. The LDLcorr is reasonable to use in patients with Lp(a) concentration ≥ 30 and ≥41 mg/dL when using the Martin-Hopkins and Sampson equations, respectively. These data may help clinicians interpret LDL-C goal attainment in patients with elevated Lp(a) and avoid misclassification driven by the Lp(a)-cholesterol component.

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Publication Details

Journal
Diseases
Published
2026-01-27
DOI
https://doi.org/10.3390/diseases14020041
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
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article

Lipoprotein(a) Concentration and Achieving Target Values of Low-Density Lipoprotein Cholesterol Calculated by Different Equations

Alexandra V. Tyurina, Sergei N. Pokrovsky, Elena A. Klesareva, Marat V. Ezhov et al.
Diseases
Lipoproteins and Cardiovascular Health
article

Lipoprotein(a) Concentration and Achieving Target Values of Low-Density Lipoprotein Cholesterol Calculated by Different Equations

Alexandra V. Tyurina, Sergei N. Pokrovsky, Elena A. Klesareva, Marat V. Ezhov, Olga I. Afanasieva
article en

Abstract

Comparison of LDL-C concentrations calculated by Friedewald, Martin-Hopkins, and Sampson equations showed high consistency in patients without elevated triglycerides. The LDLcorr is reasonable to use in patients with Lp(a) concentration ≥ 30 and ≥41 mg/dL when using the Martin-Hopkins and Sampson equations, respectively. These data may help clinicians interpret LDL-C goal attainment in patients with elevated Lp(a) and avoid misclassification driven by the Lp(a)-cholesterol component.

DiseasesVol. 14(2)
Institute of Experimental Cardiology (RU), National Medical Research Center of Cardiology (RU)
Openalex Percentile: Top 77%
Lipoproteins and Cardiovascular Health
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