Comparative Proteomics Of Hepatocytes And Hepatic Cell Lines Using Swath-MS Reveals Significant Variations In Proteins Involved In Energy, Lipid, And Xenobiotic Metabolism

This study highlights the potential of untargeted global proteomics in detecting differences in protein expression among various hepatic cell lines and provides a comprehensive database to inform the choice of the cell line in future studies.

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Publication Details

Journal
Current Drug Metabolism
Published
2026-01-22
DOI
https://doi.org/10.2174/0113892002403596251122091342
Primary Topic
Advanced Proteomics Techniques and Applications
Type
article
Field-Weighted Citation Impact
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article

Comparative Proteomics Of Hepatocytes And Hepatic Cell Lines Using Swath-MS Reveals Significant Variations In Proteins Involved In Energy, Lipid, And Xenobiotic Metabolism

Fatemeh Akhlaghi, Benjamin B Barlock, Anitha Saravanakumar, Xin Bush et al.
Current Drug Metabolism
Advanced Proteomics Techniques and Applications
article

Comparative Proteomics Of Hepatocytes And Hepatic Cell Lines Using Swath-MS Reveals Significant Variations In Proteins Involved In Energy, Lipid, And Xenobiotic Metabolism

Fatemeh Akhlaghi, Benjamin B Barlock, Anitha Saravanakumar, Xin Bush, Rohitash Jamwal
article en

Abstract

This study highlights the potential of untargeted global proteomics in detecting differences in protein expression among various hepatic cell lines and provides a comprehensive database to inform the choice of the cell line in future studies.

Current Drug MetabolismVol. 27
University of Rhode Island (US)
Affordable and clean energy
Openalex Percentile: Top 77%
Advanced Proteomics Techniques and Applications
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