Chronic Kidney Disease and Risk of Diabetic Ketoacidosis in Type 1 Diabetes

A reduced eGFR (between 30 and 90 mL/min/1.73 m2) alone was not associated with increased DKA risk. This finding supports further research into potential kidney-protection benefits of SGLTi for selected individuals with type 1 diabetes.

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Publication Details

Journal
Diabetes Care
Published
2026-01-27
DOI
https://doi.org/10.2337/dc25-1955
Primary Topic
Diabetes and associated disorders
Type
article
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article

Chronic Kidney Disease and Risk of Diabetic Ketoacidosis in Type 1 Diabetes

Aman Saleemi, Priya Bapat, Bruce A. Perkins, Dalton Budhram et al.
Diabetes Care
Diabetes and associated disorders
article

Chronic Kidney Disease and Risk of Diabetic Ketoacidosis in Type 1 Diabetes

Aman Saleemi, Priya Bapat, Bruce A. Perkins, Dalton Budhram, Andrej Orszag, Leif Erik Lovblom, Mary Rose Waniss, Natasha J. Verhoeff, Alanna Weisman, George Tomlinson, Doug Mumford, Yucheng Zhang, David Z.I. Cherney, Wajeeha Cheema, Abdulmohsen Bakhsh, Michael Fralick, Mohammad I. Abuabat, Jean-Philippe Ouimet
article en

Abstract

A reduced eGFR (between 30 and 90 mL/min/1.73 m2) alone was not associated with increased DKA risk. This finding supports further research into potential kidney-protection benefits of SGLTi for selected individuals with type 1 diabetes.

Diabetes CareVol. 49(3)
University Health Network (CA), King Saud bin Abdulaziz University for Health Sciences (SA), University of Toronto (CA), Wayne State University (US), Lunenfeld-Tanenbaum Research Institute (CA), King Faisal Specialist Hospital & Research Centre (SA), Diabetes Canada (CA), Prince Mohammed bin Abdulaziz Hospital (SA), Sinai Health System (CA), King Abdulaziz Hospital (SA), Institute for Work & Health (CA)
Good health and well-being
Openalex Percentile: Top 72%
Diabetes and associated disorders
DOISourceOpenAlex
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Chronic Kidney Disease and Risk of Diabetic Ketoacidosis in Type 1 Diabetes — Aman Saleemi, Priya Bapat, et al. · Diabetes Care (2026) | TGRS Research Map | TGRS