Trihaloisocyanuric acids: useful reagents for oxidative cyclization of diols to lactones
Abstract A novel and convenient procedure for the oxidative cyclization of diols to the corresponding lactones was achieved using trichloro- and tribromoisocyanuric acids. The methodology provided 5–11-membered lactones in 50–98% yield under simple and mild conditions. A reaction pathway is proposed by experimental evidence and DFT calculations at M062x/6-311G(d,p) level. Graphical abstract
Authors
- Marcio C. S. de Mattos
- Carlos Vinícius P. dos Santos
- Raphael C. Alves
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Universidade Federal Rural do Rio de Janeiro (BR)
Publication Details
- Journal
- Monatshefte für Chemie - Chemical Monthly
- Published
- 2026-01-27
- DOI
- https://doi.org/10.1007/s00706-026-03432-x
- Citations
- 1
- Primary Topic
- Vanadium and Halogenation Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 15.47
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro