Dibutyryl Cyclic AMP Attenuates Cerebral Ischemia-reperfusion Injury by Inhibiting Cuproptosis: A Preliminary Study
This study provides initial evidence that dBcAMP-mediated neuroprotection involves the reduction of intracellular copper overload and preservation of mitochondrial integrity, pointing to cuproptosis inhibition as a promising mechanism for future therapeutic exploration.
Authors
- Zefeng Meng
- Zhiquan Jiang
- Longjie Cai
- Yesen Zhang
- Xialin Zheng
- Shuhua Li
- Tianyang Wu
Institutions
- Guilin Medical University (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- Current Neurovascular Research
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2174/0115672026458138251211073956
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00