Anaplastic large T cell lymphoma presenting in the parotid gland: a diagnostic challenge

Abstract Background Non-Hodgkin lymphomas are a group of hematological malignancies that result from the uncontrolled proliferation of lymphoid cells. These malignancies are classified into different types based on histological structure and tumor cell type. This work describes a rare case of anaplastic large T cell lymphoma in an unusual anatomic location, the parotid gland. We have reported this case not through the classical presentation of patient information. Instead, we used the immunohistochemical description of the biopsy. Results The immunohistochemical study of parotid gland biopsy revealed an anaplastic large cell T-lymphoma with a CD3+, CD30+, and ALK− phenotype. Conclusion Anaplastic large cell lymphoma is a rare type of lymphoma. Its localization in the parotid gland is even rarer.

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Publication Details

Journal
The Egyptian Journal of Otolaryngology
Published
2026-01-27
DOI
https://doi.org/10.1186/s43163-026-01011-9
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
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article

Anaplastic large T cell lymphoma presenting in the parotid gland: a diagnostic challenge

Ibtissem El Ouar, Leila Beddar, Karima Bouali, Meriem Boulechfar et al.
The Egyptian Journal of Otolaryngology
Lymphoma Diagnosis and Treatment
article

Anaplastic large T cell lymphoma presenting in the parotid gland: a diagnostic challenge

Ibtissem El Ouar, Leila Beddar, Karima Bouali, Meriem Boulechfar, Sebti Boulekzaz, Donia Lina Chenafi
article en

Abstract

Abstract Background Non-Hodgkin lymphomas are a group of hematological malignancies that result from the uncontrolled proliferation of lymphoid cells. These malignancies are classified into different types based on histological structure and tumor cell type. This work describes a rare case of anaplastic large T cell lymphoma in an unusual anatomic location, the parotid gland. We have reported this case not through the classical presentation of patient information. Instead, we used the immunohistochemical description of the biopsy. Results The immunohistochemical study of parotid gland biopsy revealed an anaplastic large cell T-lymphoma with a CD3+, CD30+, and ALK− phenotype. Conclusion Anaplastic large cell lymphoma is a rare type of lymphoma. Its localization in the parotid gland is even rarer.

The Egyptian Journal of OtolaryngologyVol. 42(1)
University Frères Mentouri Constantine 1 (DZ), École Normale Supérieure de Constantine (DZ), Université Constantine 2 (DZ)
Openalex Percentile: Top 78%
Lymphoma Diagnosis and Treatment
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Anaplastic large T cell lymphoma presenting in the parotid gland: a diagnostic challenge — Ibtissem El Ouar, Leila Beddar, et al. · The Egyptian Journal of Otolaryngology (2026) | TGRS Research Map | TGRS