Prognostic Significance of Different Endoscopic Scores in Post-Operative Crohn’s Disease and their Role in Patients with Low-Risk Features

Grading AL seems to improve the prognostic value of early endoscopic assessment in predicting postoperative clinical recurrence. Future prospective studies are required to validate these findings. Graphical Abstract available for this article. Postoperative recurrence is a prevalent issue in Crohn's disease, affecting patients' quality of life. The Rutgeerts score serves as the standard scoring system for assessing the presence and severity of endoscopic activity after surgery; however, it is often inaccurate, particularly in cases of mild inflammation or when inflammation is confined to surgical connection between two parts of the bowel (the anastomosis). This study investigated two alternative scoring systems: the POCER index and the score developed by Ueda et al. These tools offer a more comprehensive evaluation of the anastomotic area and have proven useful in predicting postoperative recurrence within 2 years post-surgery, especially when inflammation is restricted to the anastomosis. Integrating these newer scoring systems into routine clinical practice may facilitate earlier identification of patients at higher risk of recurrence, thereby aiding in the development of more personalized treatment strategies.

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Publication Details

Journal
Advances in Therapy
Published
2026-01-27
DOI
https://doi.org/10.1007/s12325-025-03466-3
Primary Topic
Inflammatory Bowel Disease
Type
article
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article

Prognostic Significance of Different Endoscopic Scores in Post-Operative Crohn’s Disease and their Role in Patients with Low-Risk Features

Gaetano Coppola, Angelo Del Gaudio, Lucrezia Laterza, Antonio Gasbarrini et al.
Advances in Therapy
Inflammatory Bowel Disease
article

Prognostic Significance of Different Endoscopic Scores in Post-Operative Crohn’s Disease and their Role in Patients with Low-Risk Features

Gaetano Coppola, Angelo Del Gaudio, Lucrezia Laterza, Antonio Gasbarrini, Alfredo Papa, Loris Riccardo Lopetuso, Luigi Carbone, Giuseppe Cuccia, Giuseppe Privitera, Daniela Pugliese, Franco Scaldaferri, Laura Parisio
article en

Abstract

Grading AL seems to improve the prognostic value of early endoscopic assessment in predicting postoperative clinical recurrence. Future prospective studies are required to validate these findings. Graphical Abstract available for this article. Postoperative recurrence is a prevalent issue in Crohn's disease, affecting patients' quality of life. The Rutgeerts score serves as the standard scoring system for assessing the presence and severity of endoscopic activity after surgery; however, it is often inaccurate, particularly in cases of mild inflammation or when inflammation is confined to surgical connection between two parts of the bowel (the anastomosis). This study investigated two alternative scoring systems: the POCER index and the score developed by Ueda et al. These tools offer a more comprehensive evaluation of the anastomotic area and have proven useful in predicting postoperative recurrence within 2 years post-surgery, especially when inflammation is restricted to the anastomosis. Integrating these newer scoring systems into routine clinical practice may facilitate earlier identification of patients at higher risk of recurrence, thereby aiding in the development of more personalized treatment strategies.

Advances in TherapyVol. 43(3)
Università Cattolica del Sacro Cuore (IT), Agostino Gemelli University Polyclinic (IT), IRCCS Humanitas Research Hospital (IT), Link Campus University (IT)
Good health and well-being
Openalex Percentile: Top 72%
Inflammatory Bowel Disease
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Prognostic Significance of Different Endoscopic Scores in Post-Operative Crohn’s Disease and their Role in Patients with Low-Risk Features — Gaetano Coppola, Angelo Del Gaudio, et al. · Advances in Therapy (2026) | TGRS Research Map | TGRS