Overexpression of the crp gene promotes biofilm formation and increases antibiotic resistance in bovine-derived Klebsiella pneumoniae
Overexpression of CRP protein promotes biofilm formation and confers resistance to cotrimoxazole in bovine-derived <i>Klebsiella pneumonia</i>, indicating that CRP-mediated biofilm formation might be a key mechanism driving the observed cotrimoxazole resistance in this strain.
Authors
- Sirun Yi
- K. Zhang
- Li Gu
- Zhicai Zuo
- Yani Liu
- Ying Zhang
- Linqi Guo
- Jiancheng Qi
Institutions
- Sichuan Agricultural University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2026-01-26
- DOI
- https://doi.org/10.3389/fmicb.2026.1766955
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China