Sodium bicarbonate application for the treatment of acute metabolic acidosis: what we know and what we still don’t know

Metabolic acidosis is common in critically ill patients and reflects a broad spectrum of underlying pathophysiological processes.Intravenous sodium bicarbonate is widely used, yet its efficacy and safety remain debated [1].

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Publication Details

Journal
Intensive Care Medicine
Published
2026-01-26
DOI
https://doi.org/10.1007/s00134-026-08314-8
Primary Topic
Renal function and acid-base balance
Type
article
Field-Weighted Citation Impact
0.00

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article

Sodium bicarbonate application for the treatment of acute metabolic acidosis: what we know and what we still don’t know

Thilo von Groote, Beatrice Brunoni, Thomas Langer
Intensive Care Medicine
Renal function and acid-base balance
article

Sodium bicarbonate application for the treatment of acute metabolic acidosis: what we know and what we still don’t know

Thilo von Groote, Beatrice Brunoni, Thomas Langer
article en

Abstract

Metabolic acidosis is common in critically ill patients and reflects a broad spectrum of underlying pathophysiological processes.Intravenous sodium bicarbonate is widely used, yet its efficacy and safety remain debated [1].

Intensive Care Medicine
Centre Hospitalier Universitaire Vaudois (CH), Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT), University Hospital Münster (DE), University of Milano-Bicocca (IT)
Deutsche Forschungsgemeinschaft, European Society of Intensive Care Medicine
Zero hunger
Openalex Percentile: Top 80%
Renal function and acid-base balance
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