Exosome-related immune signatures and peripheral blood assays predict prognosis and immunotherapy response in hepatocellular carcinoma

In this study, we identify a novel signature based on TDEI genes that has the potential to be a biomarker for predicting the prognosis and immunotherapy response for HCC. Peripheral blood tests can be used to predict the response to HCC immunotherapy. In our study, we provide an immunologic perspective for the development of precision therapy for HCC.

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Publication Details

Journal
Frontiers in Cell and Developmental Biology
Published
2026-01-26
DOI
https://doi.org/10.3389/fcell.2025.1696790
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Exosome-related immune signatures and peripheral blood assays predict prognosis and immunotherapy response in hepatocellular carcinoma

Lili Mi, Xiaoling Duan, M. Zhao, Ruolian Gao et al.
Frontiers in Cell and Developmental Biology
Ferroptosis and cancer prognosis
article

Exosome-related immune signatures and peripheral blood assays predict prognosis and immunotherapy response in hepatocellular carcinoma

Lili Mi, Xiaoling Duan, M. Zhao, Ruolian Gao, Meng Zhang, Fei Yin
article en

Abstract

In this study, we identify a novel signature based on TDEI genes that has the potential to be a biomarker for predicting the prognosis and immunotherapy response for HCC. Peripheral blood tests can be used to predict the response to HCC immunotherapy. In our study, we provide an immunologic perspective for the development of precision therapy for HCC.

Frontiers in Cell and Developmental BiologyVol. 13
Hebei Medical University (CN), Fourth Hospital of Hebei Medical University (CN)
Hebei Medical University
No poverty
Openalex Percentile: Top 78%
Ferroptosis and cancer prognosis
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