Tolerance to ischemia–reperfusion injury in laparoscopic vs. open living donor hepatectomy with intermittent hepatic inflow occlusion: a retrospective cohort study

We found no evidence that laparoscopic IHIO increases donor risk compared with open IHIO. Instead, LDH was associated with greater tolerance to IHIO-induced hepatic IR injury and lower biliary complication risk. These findings suggest IHIO can be used safely in LDH without added risk to open IHIO.

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Publication Details

Journal
International Journal of Surgery
Published
2026-01-26
DOI
https://doi.org/10.1097/js9.0000000000004723
Primary Topic
Organ Transplantation Techniques and Outcomes
Type
article
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article

Tolerance to ischemia–reperfusion injury in laparoscopic vs. open living donor hepatectomy with intermittent hepatic inflow occlusion: a retrospective cohort study

Sangbin Han, Mi Sook Gwak, Tae‐Se Kim, Jinsoo Rhu et al.
International Journal of Surgery
Organ Transplantation Techniques and Outcomes
article

Tolerance to ischemia–reperfusion injury in laparoscopic vs. open living donor hepatectomy with intermittent hepatic inflow occlusion: a retrospective cohort study

Sangbin Han, Mi Sook Gwak, Tae‐Se Kim, Jinsoo Rhu, Jae-Won Joh, Gyu-Seong Choi, Gaab Soo Kim, Jong Man Kim
article en

Abstract

We found no evidence that laparoscopic IHIO increases donor risk compared with open IHIO. Instead, LDH was associated with greater tolerance to IHIO-induced hepatic IR injury and lower biliary complication risk. These findings suggest IHIO can be used safely in LDH without added risk to open IHIO.

International Journal of Surgery
Samsung Medical Center (KR), Sungkyunkwan University (KR)
Good health and well-being
Openalex Percentile: Top 77%
Organ Transplantation Techniques and Outcomes
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