Efficacy of Low-Dose Adjunctive Methylphenidate Extended-Release on Cognition and Functioning in Individuals With Schizophrenia
While results are interpreted cautiously due to the open-label design and small sample size, this trial suggests low-dose methylphenidate ER may enhance functional capacity, specific cognitive domains, and symptoms in schizophrenia without exacerbating psychosis.
Authors
- David Attwood
- Philip Harvey (ORCID: https://orcid.org/0000-0002-0565-3102)
- Elizabeth Kozyra
- Esther Carefoot
- Fatima Al Quraish
- Fatima Iftikhar
- Naista Zhand
- Alain Labelle
- Ridha Joober
- Carrie Robertson
Institutions
- University of Miami (US)
- University of Ottawa (CA)
- Douglas Mental Health University Institute (CA)
- Royal Ottawa Mental Health Centre (CA)
Publication Details
- Journal
- Journal of Clinical Psychopharmacology
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1097/jcp.0000000000002132
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00