Metronidazole is an effective method of analgesia following haemorrhoidectomy: a systematic review and meta-analysis

This review synthesises the best available evidence to support the use of metronidazole to reduce pain after excisional haemorrhoidectomy. While both oral and topical forms appear to be beneficial, topical administration appears to have a more effective analgesic effect from post-operative day 3.

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Publication Details

Journal
International Journal of Colorectal Disease
Published
2026-01-26
DOI
https://doi.org/10.1007/s00384-025-05066-7
Citations
1
Primary Topic
Anorectal Disease Treatments and Outcomes
Type
article
Field-Weighted Citation Impact
39.15
Controls
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article

Metronidazole is an effective method of analgesia following haemorrhoidectomy: a systematic review and meta-analysis

Christina Fleming, Aaron O’Mahony, Eoghan Condon, Colin Peirce et al.
1 citations
International Journal of Colorectal Disease
Anorectal Disease Treatments and Outcomes
39.15
article

Metronidazole is an effective method of analgesia following haemorrhoidectomy: a systematic review and meta-analysis

Christina Fleming, Aaron O’Mahony, Eoghan Condon, Colin Peirce, Benjamin M. MacCurtain, J. Calvin Coffey
article en
1 citations

Abstract

This review synthesises the best available evidence to support the use of metronidazole to reduce pain after excisional haemorrhoidectomy. While both oral and topical forms appear to be beneficial, topical administration appears to have a more effective analgesic effect from post-operative day 3.

International Journal of Colorectal DiseaseVol. 41(1)
Royal College of Surgeons in Ireland (IE), University of Limerick (IE), University Hospital Waterford (IE), University Hospital Limerick (IE)
Reduced inequalities
Openalex Percentile: Top 1%
Anorectal Disease Treatments and Outcomes
39.15
DOIOpen Access PDFOpenAlex
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Metronidazole is an effective method of analgesia following haemorrhoidectomy: a systematic review and meta-analysis — Christina Fleming, Aaron O’Mahony, et al. · International Journal of Colorectal Disease (2026) | TGRS Research Map | TGRS