Left atrial strain in mitral valve disease: a comparative analysis of regurgitation and stenosis

This study elucidates the distinct impacts of mitral stenosis and regurgitation on left atrial function, as reflected by LA strain parameters. LAstrainCD emerges as a key discriminator between these conditions, highlighting differences in atrial remodeling due to pressure and volume overload. Furthermore, LAstrainCT's correlation with MR severity enhances our understanding of atrial adaptation to regurgitant volume. These findings advance the knowledge of mitral valve disease pathophysiology, providing a foundation for improved diagnostic and therapeutic strategies.

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Publication Details

Journal
BMC Cardiovascular Disorders
Published
2026-01-26
DOI
https://doi.org/10.1186/s12872-025-05427-8
Primary Topic
Cardiovascular Function and Risk Factors
Type
article
Field-Weighted Citation Impact
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article

Left atrial strain in mitral valve disease: a comparative analysis of regurgitation and stenosis

sepideh jame bozorgi, Fariba Bayat, Nahid Mohebi Saeen, Mohammad Khani
BMC Cardiovascular Disorders
Cardiovascular Function and Risk Factors
article

Left atrial strain in mitral valve disease: a comparative analysis of regurgitation and stenosis

sepideh jame bozorgi, Fariba Bayat, Nahid Mohebi Saeen, Mohammad Khani
article en

Abstract

This study elucidates the distinct impacts of mitral stenosis and regurgitation on left atrial function, as reflected by LA strain parameters. LAstrainCD emerges as a key discriminator between these conditions, highlighting differences in atrial remodeling due to pressure and volume overload. Furthermore, LAstrainCT's correlation with MR severity enhances our understanding of atrial adaptation to regurgitant volume. These findings advance the knowledge of mitral valve disease pathophysiology, providing a foundation for improved diagnostic and therapeutic strategies.

BMC Cardiovascular DisordersVol. 26(1)
Shahid Beheshti University (IR), Shahid Beheshti University of Medical Sciences (IR)
Reduced inequalities
Openalex Percentile: Top 79%
Cardiovascular Function and Risk Factors
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