Central Neuromuscular Reactivation Using Digital Mindfulness and Motor Imagery Intervention for Chronic Knee Pain in Patients With Obesity: Prospective, Single-Center Study

Video-guided motor imagery demonstrated significant efficacy in reducing pain and improving the functionality and quality of life of patients with obesity and chronic knee pain. By targeting central neuromuscular circuits through guided visualization exercises, this non-invasive intervention addresses central activation dysfunction, a proposed novel concept in neuromuscular disorders that originates from hypotheses derived from clinical observations. This interesting concept requires further exploration to ensure its neurophysiological validation through future studies with larger sample sizes, control groups, and long-term follow-ups, all of which could explore CAD as a therapeutic target.