From Clot Prevention to Kidney Injury: Revisiting Anticoagulant-Related Nephropathy

ARN is an increasingly recognized cause of AKI in anticoagulated patients, particularly those with CKD. The condition is often associated with incomplete or absent renal recovery and significantly higher mortality in non-recovering patients. Therefore, early recognition and appropriate risk stratification are crucial, although current treatment options remain largely supportive. Further research is needed to establish validated diagnostic criteria and effective therapeutic strategies.

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Publication Details

Journal
Kidney & Blood Pressure Research
Published
2026-01-26
DOI
https://doi.org/10.1159/000550599
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
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article

From Clot Prevention to Kidney Injury: Revisiting Anticoagulant-Related Nephropathy

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Kidney & Blood Pressure Research
Atrial Fibrillation Management and Outcomes
article

From Clot Prevention to Kidney Injury: Revisiting Anticoagulant-Related Nephropathy

Sandra Karanović, Nasim Wiegley, Tiffany Caza, Sayna Norouzi, Irene Martín Capón, Paolo Nikolai So, Mohamed Hassanein, Harish Seethapathy, Paul E. Hanna, Edgar Lerma
article en

Abstract

ARN is an increasingly recognized cause of AKI in anticoagulated patients, particularly those with CKD. The condition is often associated with incomplete or absent renal recovery and significantly higher mortality in non-recovering patients. Therefore, early recognition and appropriate risk stratification are crucial, although current treatment options remain largely supportive. Further research is needed to establish validated diagnostic criteria and effective therapeutic strategies.

Kidney & Blood Pressure ResearchVol. 51(1)
Piedmont Athens Regional (US), Harvard University (US), University of Zagreb (HR), Medical College of Wisconsin (US), Loma Linda University (US), University of Illinois Chicago (US), University of Chicago (US), Research Institute Hospital 12 de Octubre (ES), Arkana Laboratories (US), Kidney Associates (US), University of California, Davis (US)
Good health and well-being
Openalex Percentile: Top 79%
Atrial Fibrillation Management and Outcomes
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