Implantable Tibial Neuromodulation Therapy Improves Symptoms of Urge Urinary Incontinence from the TITAN 2 Pivotal Study
TITAN 2 met the primary and all secondary objectives by showing a statistically significant improvement of UUI, urinary frequency, and urgency symptoms. Clinical benefits and a favorable safety profile were maintained through 12 months.
Authors
- Geoffrey D. Towers (ORCID: https://orcid.org/0000-0001-9019-7529)
- Brian J. Linder (ORCID: https://orcid.org/0000-0003-4674-2598)
- Samantha Raffee (ORCID: https://orcid.org/0000-0003-1048-6297)
- Ryan M. Krlin
- Jerome L. Yaklic (ORCID: https://orcid.org/0000-0003-3336-9296)
- Nathan Grunow
- K. D. Finkelstein (ORCID: https://orcid.org/0000-0002-1851-2624)
- Hadley Narins
- Humphrey Atiemo
- Scott MacDiarmid
- Jodi Michaels
- Janet E. Harris-Hicks (ORCID: https://orcid.org/0000-0002-8869-1488)
- Jeffrey M. Carey
- Laura Giusto
- Emily Gillespie
- Elizabeth Takacs (ORCID: https://orcid.org/0000-0003-2378-7806)
- Amanda Vo
- Kevin Benson (ORCID: https://orcid.org/0000-0001-9512-7431)
- M Fischer
- Una Lee
- Jason Kim
- Keith Xavier
- Alison Pickering
- Courtenay Moore
- Annah Vollstedt
- Stephanie Kielb
- Jason Bennett
- Nicolette Deveneau
- Jeffrey Proctor
- Kimberly Burgess
- Dennis Miller
Institutions
- Virginia Mason Medical Center (US)
- The University of Texas at Arlington (US)
- Stony Brook University Hospital (US)
- Medtronic (United States) (US)
- Central Ohio Radiation Oncology (US)
- FirstHealth of the Carolinas (US)
- Institute for Female Pelvic Medicine and Reconstructive Surgery (US)
- Chesapeake Urology Associates (US)
- Carolina Urologic Research Center (US)
- HealthPartners (US)
- The University of Texas Medical Branch at Galveston (US)
Publication Details
- Journal
- The Journal of Urology
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1097/ju.0000000000004958
- Primary Topic
- Urinary Bladder and Prostate Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00