Deciphering the role of circulating inflammatory proteins in myocarditis: Novel strategies for targeted therapy

Elevated circulating LIF levels may be causally linked to increased myocarditis risk, supporting its potential as both a predictive biomarker and a therapeutic target. These results provide a rationale for further experimental studies to clarify the context-dependent roles of LIF in myocardial inflammation and to evaluate LIF-directed interventions.

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Publication Details

Journal
International Journal of Cardiology
Published
2026-01-26
DOI
https://doi.org/10.1016/j.ijcard.2026.134198
Primary Topic
Viral Infections and Immunology Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Deciphering the role of circulating inflammatory proteins in myocarditis: Novel strategies for targeted therapy

Zhiyu Zhang, Haiyang Xie, Yifan Chen, Hailu Wang et al.
International Journal of Cardiology
Viral Infections and Immunology Research
article

Deciphering the role of circulating inflammatory proteins in myocarditis: Novel strategies for targeted therapy

Zhiyu Zhang, Haiyang Xie, Yifan Chen, Hailu Wang, Fajar Prasetya, Zeye Liu, Xi Chen, Qi Li, Ke Li, Yiyin Zhang
article en

Abstract

Elevated circulating LIF levels may be causally linked to increased myocarditis risk, supporting its potential as both a predictive biomarker and a therapeutic target. These results provide a rationale for further experimental studies to clarify the context-dependent roles of LIF in myocardial inflammation and to evaluate LIF-directed interventions.

International Journal of CardiologyVol. 449
Fujian Medical University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking University (CN), Kunming Medical University (CN), Peking Union Medical College Hospital (CN), Shanghai Cancer Institute (CN), First Affiliated Hospital of Kunming Medical University (CN), Peking University People's Hospital (CN), Peking University First Hospital (CN), Fu Wai Hospital (CN), Mulawarman University (ID)
Good health and well-being
Openalex Percentile: Top 79%
Viral Infections and Immunology Research
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Deciphering the role of circulating inflammatory proteins in myocarditis: Novel strategies for targeted therapy — Zhiyu Zhang, Haiyang Xie, et al. · International Journal of Cardiology (2026) | TGRS Research Map | TGRS