Not always autoimmune hepatitis: Hepatic steatosis is associated with autoantibodies positivity in patients with hepatocellular dysfunction

AIH was not confirmed in 47% of patients with liver dysfunction and positive autoantibodies. Multivariate analysis identified male gender and elevated CAP values as independent predictive factors for a non-confirmed diagnosis of AIH in patients with liver dysfunction and ANA positivity. Further prospective and multicenter validation is required in order to corroborate our findings.

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Publication Details

Journal
World Journal of Hepatology
Published
2026-01-27
DOI
https://doi.org/10.4254/wjh.v18.i1.114045
Primary Topic
Liver Diseases and Immunity
Type
article
Field-Weighted Citation Impact
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article

Not always autoimmune hepatitis: Hepatic steatosis is associated with autoantibodies positivity in patients with hepatocellular dysfunction

Ana Isabel Ferreira, Mariana Costa Azevedo, José Cotter, Sofia Xavier et al.
World Journal of Hepatology
Liver Diseases and Immunity
article

Not always autoimmune hepatitis: Hepatic steatosis is associated with autoantibodies positivity in patients with hepatocellular dysfunction

Ana Isabel Ferreira, Mariana Costa Azevedo, José Cotter, Sofia Xavier, Vitor Macedo Silva, Joana Magalhães
article en

Abstract

AIH was not confirmed in 47% of patients with liver dysfunction and positive autoantibodies. Multivariate analysis identified male gender and elevated CAP values as independent predictive factors for a non-confirmed diagnosis of AIH in patients with liver dysfunction and ANA positivity. Further prospective and multicenter validation is required in order to corroborate our findings.

World Journal of HepatologyVol. 18(1)
Administração Regional de Saúde de Lisboa e Vale do Tejo (PT), University of Minho (PT)
No poverty
Openalex Percentile: Top 75%
Liver Diseases and Immunity
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