Comparison of delayed versus immediate coloanal anastomosis in patients with low rectal cancer: a recent meta-analysis

Compared with ICA, DCA is associated with significantly lower risks of overall complications, anastomotic complications, and anastomotic leakage in sphincter-preserving surgery for LRC, without compromising oncological safety. It demonstrates comparable performance in core perioperative indicators and may offer particular advantages for patients seeking minimally invasive approaches, those unable to tolerate stomas, or those at high risk of anastomotic failure. Therefore, DCA represents a viable and potentially preferable surgical option in the management of LRC. This study strictly adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and was registered on the PROSPERO international systematic review registration platform (registration number: CRD420251233006).

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-26
DOI
https://doi.org/10.3389/fonc.2025.1749894
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparison of delayed versus immediate coloanal anastomosis in patients with low rectal cancer: a recent meta-analysis

Jiangpeng Li, Jie Dan, Ke Liu, Lei Chen et al.
Frontiers in Oncology
Colorectal Cancer Surgical Treatments
article

Comparison of delayed versus immediate coloanal anastomosis in patients with low rectal cancer: a recent meta-analysis

Jiangpeng Li, Jie Dan, Ke Liu, Lei Chen, Yonghong Wang, Mingjie Zhu, Ming Li, Wanbin He, Wenjie Zhou
article en

Abstract

Compared with ICA, DCA is associated with significantly lower risks of overall complications, anastomotic complications, and anastomotic leakage in sphincter-preserving surgery for LRC, without compromising oncological safety. It demonstrates comparable performance in core perioperative indicators and may offer particular advantages for patients seeking minimally invasive approaches, those unable to tolerate stomas, or those at high risk of anastomotic failure. Therefore, DCA represents a viable and potentially preferable surgical option in the management of LRC. This study strictly adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and was registered on the PROSPERO international systematic review registration platform (registration number: CRD420251233006).

Frontiers in OncologyVol. 15
Leshan Normal University (CN)
Good health and well-being
Openalex Percentile: Top 77%
Colorectal Cancer Surgical Treatments
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