Quantitative MRI Findings and Their Relationship to Muscle Histopathology and Ambulatory Clinical Function in Duchenne Muscular Dystrophy

Our study demonstrates a significant relationship between muscle FF on IDEAL-IQ MRI and histopathologic muscle fatty infiltration, as well as ambulatory clinical function in DMD. DMD patients exhibit a distinct and inhomogeneous fat infiltration pattern of lower limb muscles.

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Publication Details

Journal
Journal of Cachexia Sarcopenia and Muscle
Published
2026-01-25
DOI
https://doi.org/10.1002/jcsm.70205
Primary Topic
Muscle Physiology and Disorders
Type
article
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article

Quantitative MRI Findings and Their Relationship to Muscle Histopathology and Ambulatory Clinical Function in Duchenne Muscular Dystrophy

Changli Liu, Xiao Jx, Qiang Gang, Zi Wang et al.
Journal of Cachexia Sarcopenia and Muscle
Muscle Physiology and Disorders
article

Quantitative MRI Findings and Their Relationship to Muscle Histopathology and Ambulatory Clinical Function in Duchenne Muscular Dystrophy

Changli Liu, Xiao Jx, Qiang Gang, Zi Wang, Wen Zhang, Lingchao Meng, Lixue Yin, Zhiying Xie, Yun Yuan, Zhihao Xie, Siwei Chen, Qingyue Yuan, Jianan Liao, Yawen Zhao
article en

Abstract

Our study demonstrates a significant relationship between muscle FF on IDEAL-IQ MRI and histopathologic muscle fatty infiltration, as well as ambulatory clinical function in DMD. DMD patients exhibit a distinct and inhomogeneous fat infiltration pattern of lower limb muscles.

Journal of Cachexia Sarcopenia and MuscleVol. 17(1)
University of Science and Technology of China (CN), Peking University (CN), Peking University First Hospital (CN), Yangzhou University (CN)
Openalex Percentile: Top 77%
Muscle Physiology and Disorders
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Quantitative MRI Findings and Their Relationship to Muscle Histopathology and Ambulatory Clinical Function in Duchenne Muscular Dystrophy — Changli Liu, Xiao Jx, et al. · Journal of Cachexia Sarcopenia and Muscle (2026) | TGRS Research Map | TGRS