Comparative efficacy of reinforced suturing, transanal drainage tube, and no additional intervention in preventing anastomotic leakage after rectal cancer surgery: a network meta-analysis

Both RS and TDT were associated with a reduction in overall AL risk compared to NRT. Network estimates suggested that RS may be more effective than TDT in preventing the more severe Grade C AL; however, this finding is based on indirect comparisons with wide credible intervals and requires confirmation in future head-to-head trials. The choice of intervention may therefore depend on patient risk profile and clinical context.