Patent Foramen Ovale Closure in Stroke and the PASCAL Classification System
Among young and middle-aged patients with PFO and otherwise cryptogenic stroke, the PASCAL classification algorithm distinguished the 4 of every 5 patients in the probable and possible groups with net benefit and the 1 of every 5 patients in the unlikely group with net harm from closure.
Authors
- David M. Kent (ORCID: https://orcid.org/0000-0002-9205-5070)
- JL Mas
- Benjamin Koethe (ORCID: https://orcid.org/0000-0001-8019-181X)
- B. Meier
- Mark Reisman
- J. Carroll
- Bénédicte Lefebvre (ORCID: https://orcid.org/0000-0002-8587-7279)
- S. E. Kasner
- Richard W. Smalling (ORCID: https://orcid.org/0000-0002-3516-7789)
- Jason Nelson
- Peter Jni
- Gilles Châtellier (ORCID: https://orcid.org/0000-0002-6373-8956)
- Lars Søndergaard
- Jae-Kwan Song
- Pil Hyung Lee
- Heinrich P. Mattle
- Jeffrey L. Saver
- Howard C. Herrmann
- Anthony J. Furlan
- Jong S. Kim
- David E. Thaler
Institutions
- Ulsan College (KR)
- Tufts University (US)
- University of Copenhagen (DK)
- Tufts Medical Center (US)
- St. Michael's Hospital (CA)
- University of California, Los Angeles (US)
- University of Toronto (CA)
- University Hospital of Bern (CH)
- Asan Medical Center (KR)
- University of Washington Medical Center (US)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- University of Ulsan (KR)
- Hôpital Européen (FR)
- Institut de Psychiatrie et Neurosciences de Paris (FR)
- Oxford Applied Research (United Kingdom) (GB)
- FHU Neurovasc (FR)
- Oxford BioMedica (United Kingdom) (GB)
- Case Western Reserve University (US)
- University of Pennsylvania (US)
- The University of Texas Health Science Center at Houston (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- JAMA Neurology
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1001/jamaneurol.2025.5446
- Citations
- 1
- Primary Topic
- Cardiovascular and Diving-Related Complications
- Type
- article
- Field-Weighted Citation Impact
- 36.44