Prevalence of High-Risk Human Papillomavirus in Squamous Cell Carcinomas of the Lacrimal Sac

Primary lacrimal sac SCCs are frequently associated with HR-HPV and typically show nonkeratinizing, papillary morphology. p16 is a reliable surrogate marker for transcriptionally active HR-HPV in these tumors, supporting a potential etiologic role and diagnostic utility.

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Publication Details

Journal
Ophthalmic Plastic and Reconstructive Surgery
Published
2026-01-26
DOI
https://doi.org/10.1097/iop.0000000000003186
Primary Topic
Nasolacrimal Duct Obstruction Treatments
Type
article
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article

Prevalence of High-Risk Human Papillomavirus in Squamous Cell Carcinomas of the Lacrimal Sac

Carmen Gomez‐Fernandez, Jaylou M. Velez-Torres, Sander R. Dubovy, Yoseph Sayegh et al.
Ophthalmic Plastic and Reconstructive Surgery
Nasolacrimal Duct Obstruction Treatments
article

Prevalence of High-Risk Human Papillomavirus in Squamous Cell Carcinomas of the Lacrimal Sac

Carmen Gomez‐Fernandez, Jaylou M. Velez-Torres, Sander R. Dubovy, Yoseph Sayegh, Maria Alejandra Idarraga, Drew Baeza, Miguel Hernández
article en

Abstract

Primary lacrimal sac SCCs are frequently associated with HR-HPV and typically show nonkeratinizing, papillary morphology. p16 is a reliable surrogate marker for transcriptionally active HR-HPV in these tumors, supporting a potential etiologic role and diagnostic utility.

Ophthalmic Plastic and Reconstructive Surgery
University of Miami (US), Minnesota Lions Eye Bank (US)
Gender equality
Openalex Percentile: Top 78%
Nasolacrimal Duct Obstruction Treatments
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