HMG-CoA Reductase Inhibitors (Statins) May Preserve Hepatic Function and Reduce Portal-Systemic Shunting in Compensated Advanced Chronic Liver Disease: Results From the SHUNT-V Study
Concomitant use of statins alone or in combination with metformin was independently associated with preserved hepatic function (DSI) and reduced portal-systemic shunting (SHUNT%).
Authors
- Joanne C. Imperial
- John Kittelson (ORCID: https://orcid.org/0000-0002-4929-1414)
- Kathryn Jean Lucas (ORCID: https://orcid.org/0000-0003-1197-1403)
- Michael P. McRae (ORCID: https://orcid.org/0000-0002-2126-9442)
- Gregory T. Everson (ORCID: https://orcid.org/0000-0003-0454-3566)
- Robert S. Rahimi (ORCID: https://orcid.org/0000-0002-2595-1852)
- Alastair D. Smith
- Edward Mena
- for the SHUNT-V Subjects, Investigators, and Coordinators
Institutions
- Carteret Community College (US)
- Custom Electronics (United States) (US)
- Lucas Research (US)
- Syneos Health (United States) (US)
- California Liver Research Institute (US)
- ColdQuanta, Inc., DBA Infleqtion (United States) (US)
- Baylor Scott & White Health (US)
Publication Details
- Journal
- Clinical and Translational Gastroenterology
- Published
- 2026-01-26
- DOI
- https://doi.org/10.14309/ctg.0000000000000980
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00