Tumor cell invasion of blood vessels predicts poor survival in upper tract urothelial carcinoma following radical nephroureterectomy
Distinguishing BVI from LymVI provides refined prognostic stratification in UTUC. BVI, alone or combined with LymVI, is strongly associated with adverse survival and increased hematogenous dissemination, while isolated LymVI has limited prognostic impact. Routine pathological subclassification of vascular invasion may improve postoperative risk assessment and guide adjuvant treatment decisions.
Authors
- Miyaka Umemori
- Masaya Murakami (ORCID: https://orcid.org/0000-0002-1268-6615)
- Yuzo. Inaba
- Masayuki Shimoda (ORCID: https://orcid.org/0000-0003-4929-6546)
- Mahito Atsuta
- Yuya Iwamoto (ORCID: https://orcid.org/0009-0009-1396-3192)
- Shun Sato (ORCID: https://orcid.org/0000-0002-1650-6239)
- Juria Nakano
- Shuhei Hara
- Kojiro Tashiro
- Yu Imai
- Wataru Fukuokaya
- Shunsuke Tsuzuki
- Kosuke Iwatani
- Hirotaka Kondo
- Kentaro Yoshihara
- Jun Miki
- Takahiro Kimura
- Hiroyuki Takahashi
Institutions
- Jikei University School of Medicine (JP)
- Juntendo University (JP)
- Katsushika Medical Center (JP)
- Fujieda Municipal General Hospital (JP)
- Juntendo University Urayasu Hospital (JP)
- Jikei University Kashiwa hospital (JP)
- JR Tokyo General Hospital (JP)
- Tsurugi Hospital (JP)
Publication Details
- Journal
- Japanese Journal of Clinical Oncology
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1093/jjco/hyag002
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00