Transforming growth factor beta reduces proprotein convertase subtilisin/kexin type 9 in the supernatant of hepatic stellate cells

Profibrotic TGF-β and the antifibrotic liver X receptor ligand both reduced PCSK9 in LX-2 medium, showing that PCSK9 is not a marker of HSC activation.

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Publication Details

Journal
World Journal of Hepatology
Published
2026-01-27
DOI
https://doi.org/10.4254/wjh.v18.i1.113896
Primary Topic
Liver physiology and pathology
Type
article
Field-Weighted Citation Impact
0.00
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article

Transforming growth factor beta reduces proprotein convertase subtilisin/kexin type 9 in the supernatant of hepatic stellate cells

Marlen Spirk, Maximilian Neumann, Sebastian Zimny, Jan Bundschuh et al.
World Journal of Hepatology
Liver physiology and pathology
article

Transforming growth factor beta reduces proprotein convertase subtilisin/kexin type 9 in the supernatant of hepatic stellate cells

Marlen Spirk, Maximilian Neumann, Sebastian Zimny, Jan Bundschuh, Christa Buechler
article en

Abstract

Profibrotic TGF-β and the antifibrotic liver X receptor ligand both reduced PCSK9 in LX-2 medium, showing that PCSK9 is not a marker of HSC activation.

World Journal of HepatologyVol. 18(1)
University Hospital Regensburg (DE)
Openalex Percentile: Top 75%
Liver physiology and pathology
DOIOpen Access PDFOpenAlex
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Transforming growth factor beta reduces proprotein convertase subtilisin/kexin type 9 in the supernatant of hepatic stellate cells — Marlen Spirk, Maximilian Neumann, et al. · World Journal of Hepatology (2026) | TGRS Research Map | TGRS