<scp>GLP</scp> ‐ <scp>1RAs</scp> versus metformin and Parkinson's risk in type 2 diabetes

By addressing key limitations of earlier studies through a large-scale, active-comparator, new-user design, this study provides novel evidence of a delayed neuroprotective effect of GLP-1RAs. These findings support incorporating neurologic outcomes into long-term diabetes management and may inform therapy selection in high-risk populations.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2026-01-26
DOI
https://doi.org/10.1111/dom.70459
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

GLP ‐ 1RAs versus metformin and Parkinson's risk in type 2 diabetes

J. Zhang, Wan‐Ming Chen, Xiaoling Wang, Tian Mao et al.
Diabetes Obesity and Metabolism
Diabetes Treatment and Management
article

GLP ‐ 1RAs versus metformin and Parkinson's risk in type 2 diabetes

J. Zhang, Wan‐Ming Chen, Xiaoling Wang, Tian Mao, Zhongyuan Lu, Szu‐Yuan Wu, Shuang Lv, Mingyang Sun
article en

Abstract

By addressing key limitations of earlier studies through a large-scale, active-comparator, new-user design, this study provides novel evidence of a delayed neuroprotective effect of GLP-1RAs. These findings support incorporating neurologic outcomes into long-term diabetes management and may inform therapy selection in high-risk populations.

Diabetes Obesity and MetabolismVol. 28(4)
Fu Jen Catholic University (TW), Asia University (TW), Luodong Poh-Ai Hospital (TW), Zhengzhou University (CN), Henan Academy of Sciences (CN), Henan Provincial People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 79%
Diabetes Treatment and Management
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